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Nutrient supplementation strategy improves cell concentration and longevity, monoclonal antibody production and lactate metabolism of Chinese hamster ovary cells

A careful selection of culture mediums and feeds has become necessary to maximize yields of recombinant proteins during bioprocesses of mammalian cells. Supplements contain a variety of concentrate nutrients, and their beneficial effects vary according to recombinant cell lines. In this study, the e...

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Detalles Bibliográficos
Autores principales: Pérez-Rodriguez, Saumel, Ramírez-Lira, María de Jesús, Trujillo-Roldán, Mauricio A., Valdez-Cruz, Norma A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161567/
https://www.ncbi.nlm.nih.gov/pubmed/32223359
http://dx.doi.org/10.1080/21655979.2020.1744266