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Beyond DNA Damage: Exploring the Immunomodulatory Effects of Cyclophosphamide in Multiple Myeloma

The alkylating agent cyclophosphamide has been used in the treatment of multiple myeloma for over 60 years. At low doses, cyclophosphamide also has significant immunomodulatory activity, which can be used to modify the immunosuppressive tumor microenvironment in order to augment responses to existin...

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Detalles Bibliográficos
Autores principales: Swan, Dawn, Gurney, Mark, Krawczyk, Janusz, Ryan, Aideen E., O’Dwyer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162079/
https://www.ncbi.nlm.nih.gov/pubmed/32309787
http://dx.doi.org/10.1097/HS9.0000000000000350