FANCJ helicase promotes DNA end resection by facilitating CtIP recruitment to DNA double-strand breaks

FANCJ helicase mutations are known to cause hereditary breast and ovarian cancers as well as bone marrow failure syndrome Fanconi anemia. FANCJ plays an important role in the repair of DNA inter-strand crosslinks and DNA double-strand breaks (DSBs) by homologous recombination (HR). Nonetheless, the...

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Detalles Bibliográficos
Autores principales: Nath, Sarmi, Nagaraju, Ganesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162537/
https://www.ncbi.nlm.nih.gov/pubmed/32251466
http://dx.doi.org/10.1371/journal.pgen.1008701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162537/
https://www.ncbi.nlm.nih.gov/pubmed/32251466
http://dx.doi.org/10.1371/journal.pgen.1008701

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