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Fluorescence fluctuation analysis reveals PpV dependent Cdc25 protein dynamics in living embryos

The protein phosphatase Cdc25 is a key regulator of the cell cycle by activating Cdk-cyclin complexes. Cdc25 is regulated by its expression levels and post-translational mechanisms. In early Drosophila embryogenesis, Cdc25/Twine drives the fast and synchronous nuclear cycles. A pause in the cell cyc...

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Detalles Bibliográficos
Autores principales: Liu, Boyang, Gregor, Ingo, Müller, H.-Arno, Großhans, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162543/
https://www.ncbi.nlm.nih.gov/pubmed/32251417
http://dx.doi.org/10.1371/journal.pgen.1008735