Cargando…
Complementary computational and experimental evaluation of missense variants in the ROMK potassium channel
The renal outer medullary potassium (ROMK) channel is essential for potassium transport in the kidney, and its dysfunction is associated with a salt-wasting disorder known as Bartter syndrome. Despite its physiological significance, we lack a mechanistic understanding of the molecular defects in ROM...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162551/ https://www.ncbi.nlm.nih.gov/pubmed/32251469 http://dx.doi.org/10.1371/journal.pcbi.1007749 |