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Network mechanisms and dysfunction within an integrated computational model of progression through mitosis in the human cell cycle
The cellular protein-protein interaction network that governs cellular proliferation (cell cycle) is highly complex. Here, we have developed a novel computational model of human mitotic cell cycle, integrating diverse cellular mechanisms, for the purpose of generating new hypotheses and predicting n...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162553/ https://www.ncbi.nlm.nih.gov/pubmed/32251461 http://dx.doi.org/10.1371/journal.pcbi.1007733 |