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SAD-B modulates epileptic seizure by regulating AMPA receptors in patients with temporal lobe epilepsy and in the PTZ-induced epileptic model

α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are the predominant mediators of glutamate-induced excitatory neurotransmission. It is widely accepted that AMPA receptors are critical for the generation and spread of epileptic seizure activity. Dysfunction of AMPA receptors as...

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Detalles Bibliográficos
Autores principales: Li, Rong, He, Miaoqing, Wu, Bing, Zhang, Peng, Zhang, Qinbin, Chen, Yangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162585/
https://www.ncbi.nlm.nih.gov/pubmed/32267308
http://dx.doi.org/10.1590/1414-431X20199175