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Mycobacterium tuberculosis exploits host ATM kinase for survival advantage through SecA2 secretome

(Mtb) produces inflections in the host signaling networks to create a favorable milieu for survival. The virulent Mtb strain, Rv caused double strand breaks (DSBs), whereas the non-virulent Ra strain triggered single-stranded DNA generation. The effectors secreted by SecA2 pathway were essential and...

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Detalles Bibliográficos
Autores principales: Lochab, Savita, Singh, Yogendra, Sengupta, Sagar, Nandicoori, Vinay Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162654/
https://www.ncbi.nlm.nih.gov/pubmed/32223892
http://dx.doi.org/10.7554/eLife.51466