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SKA1 regulates actin cytoskeleton remodelling via activating Cdc42 and influences the migration of pancreatic ductal adenocarcinoma cells

OBJECTIVES: Spindle and kinetochore–associated protein 1(SKA1), originally identified as a protein essential for proper chromosome segregation, has been recently linked to multiple malignancies. This study aimed to explore the biological, clinical role and molecular mechanism of SKA1 in pancreatic c...

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Detalles Bibliográficos
Autores principales: Li, Tong, Liu, Xu, Xu, Bin, Wu, Wei, Zang, Yi, Li, Juanjuan, Wei, Lumin, Qian, Yuting, Xu, Hui, Xie, Mingping, Wang, Qi, Wang, Lifu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162805/
https://www.ncbi.nlm.nih.gov/pubmed/32232899
http://dx.doi.org/10.1111/cpr.12799