Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines

INTRODUCTION: Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) mutations occur in approximately one-third of colorectal (CRC) tumours and have been associated with poor prognosis and resistance to some therapeutics. In addition to the well-documented pro-tumorigenic role of mutant Ras alleles, ther...

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Detalles Bibliográficos
Autores principales: Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C., Everett, Jeremy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162829/
https://www.ncbi.nlm.nih.gov/pubmed/32300895
http://dx.doi.org/10.1007/s11306-020-01674-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162829/
https://www.ncbi.nlm.nih.gov/pubmed/32300895
http://dx.doi.org/10.1007/s11306-020-01674-2

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