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Pseudo-Symmetric Assembly of Protodomains as a Common Denominator in the Evolution of Polytopic Helical Membrane Proteins

The polytopic helical membrane proteome is dominated by proteins containing seven transmembrane helices (7TMHs). They cannot be grouped under a monolithic fold or superfold. However, a parallel structural analysis of folds around that magic number of seven in distinct protein superfamilies (SWEET, P...

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Detalles Bibliográficos
Autores principales: Youkharibache, Philippe, Tran, Alexander, Abrol, Ravinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162841/
https://www.ncbi.nlm.nih.gov/pubmed/32189026
http://dx.doi.org/10.1007/s00239-020-09934-4