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CDDO-Me Alters the Tumor Microenvironment in Estrogen Receptor Negative Breast Cancer

The tumor microenvironment (TME) is an essential contributor to the development and progression of malignancy. Within the TME, tumor associated macrophages (TAMs) mediate angiogenesis, metastasis, and immunosuppression, which inhibits infiltration of tumor-specific cytotoxic CD8+ T cells. In previou...

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Detalles Bibliográficos
Autores principales: Ball, Michael S., Bhandari, Rajan, Torres, Gretel M., Martyanov, Viktor, ElTanbouly, Mohamed A., Archambault, Kim, Whitfield, Michael L., Liby, Karen T., Pioli, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162855/
https://www.ncbi.nlm.nih.gov/pubmed/32300202
http://dx.doi.org/10.1038/s41598-020-63482-x