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CDDO-Me Alters the Tumor Microenvironment in Estrogen Receptor Negative Breast Cancer
The tumor microenvironment (TME) is an essential contributor to the development and progression of malignancy. Within the TME, tumor associated macrophages (TAMs) mediate angiogenesis, metastasis, and immunosuppression, which inhibits infiltration of tumor-specific cytotoxic CD8+ T cells. In previou...
Autores principales: | Ball, Michael S., Bhandari, Rajan, Torres, Gretel M., Martyanov, Viktor, ElTanbouly, Mohamed A., Archambault, Kim, Whitfield, Michael L., Liby, Karen T., Pioli, Patricia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162855/ https://www.ncbi.nlm.nih.gov/pubmed/32300202 http://dx.doi.org/10.1038/s41598-020-63482-x |
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