Repurposing a platelet aggregation inhibitor ticagrelor as an antimicrobial against Clostridioides difficile

Drug resistance in Clostridioides difficile becomes a public health concern worldwide, especially as the hypervirulent strains show decreased susceptibility to the first-line antibiotics for C. difficile treatment. Therefore, the simultaneous discovery and development of new compounds to fight this...

Descripción completa

Detalles Bibliográficos
Autores principales: Phanchana, Matthew, Phetruen, Tanaporn, Harnvoravongchai, Phurt, Raksat, Ponlawoot, Ounjai, Puey, Chankhamhaengdecha, Surang, Janvilisri, Tavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162883/
https://www.ncbi.nlm.nih.gov/pubmed/32300130
http://dx.doi.org/10.1038/s41598-020-63199-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162883/
https://www.ncbi.nlm.nih.gov/pubmed/32300130
http://dx.doi.org/10.1038/s41598-020-63199-x

Ejemplares similares