Founder BRCA1/BRCA2/PALB2 pathogenic variants in French-Canadian breast cancer cases and controls

Inherited germline pathogenic variants are responsible for ~5% of breast cancer globally. Through rapid expansion and isolation since immigration in the early 17(th) century, French Canadians are a relatively genetically homogenous founder population and therefore represent a unique demographic for...

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Detalles Bibliográficos
Autores principales: Behl, Supriya, Hamel, Nancy, de Ladurantaye, Manon, Lepage, Stéphanie, Lapointe, Réjean, Mes-Masson, Anne-Marie, Foulkes, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162921/
https://www.ncbi.nlm.nih.gov/pubmed/32300229
http://dx.doi.org/10.1038/s41598-020-63100-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162921/
https://www.ncbi.nlm.nih.gov/pubmed/32300229
http://dx.doi.org/10.1038/s41598-020-63100-w

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