MSC-induced lncRNA HCP5 drove fatty acid oxidation through miR-3619-5p/AMPK/PGC1α/CEBPB axis to promote stemness and chemo-resistance of gastric cancer

Chemotherapy is the first-tier treatment regime for gastric cancer (GC) patients at advance stages. Mesenchymal stem cell (MSC) cam affect drug-resistance of GC cells in tumor microenvironment, but the detailed mechanism remains poorly understood. Present study aimed to investigate the regulation of...

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Detalles Bibliográficos
Autores principales: Wu, Honglei, Liu, Bin, Chen, Zhaosheng, Li, Guangchun, Zhang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162922/
https://www.ncbi.nlm.nih.gov/pubmed/32300102
http://dx.doi.org/10.1038/s41419-020-2426-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162922/
https://www.ncbi.nlm.nih.gov/pubmed/32300102
http://dx.doi.org/10.1038/s41419-020-2426-z

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