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Metabolic basis of neuronal vulnerability to ischemia; an in vivo untargeted metabolomics approach
Understanding the root causes of neuronal vulnerability to ischemia is paramount to the development of new therapies for stroke. Transient global cerebral ischemia (tGCI) leads to selective neuronal cell death in the CA1 sub-region of the hippocampus, while the neighboring CA3 sub-region is left lar...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162929/ https://www.ncbi.nlm.nih.gov/pubmed/32300196 http://dx.doi.org/10.1038/s41598-020-63483-w |