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Acquired Uniparental Disomy Regions Are Associated with Disease Outcome in Patients with Oral Cavity and Oropharynx But Not Larynx Cancers

Acquired uniparental disomy (aUPD) regions pinpoint homozygousity and monoallelic expressed genes. We analyzed The Cancer Genome Atlas single-nucleotide polymorphism arrays and expression data from oral cavity, oropharynx, and larynx cancers to identify frequency of aUPD in each tumor type and assoc...

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Detalles Bibliográficos
Autores principales: Tuna, Musaffe, I. Amos, Christopher, B. Mills, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163079/
https://www.ncbi.nlm.nih.gov/pubmed/32305020
http://dx.doi.org/10.1016/j.tranon.2020.100763