Local delivery of dinutuximab from lyophilized silk fibroin foams for treatment of an orthotopic neuroblastoma model

Immunotherapy targeting GD2 is a primary treatment for patients with high‐risk neuroblastoma. Dinutuximab is a monoclonal antibody with great clinical promise but is limited by side effects such as severe pain. Local delivery has emerged as a potential mechanism to deliver higher doses of therapeuti...

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Detalles Bibliográficos
Autores principales: Ornell, Kimberly J., Taylor, Jordan S., Zeki, Jasmine, Ikegaki, Naohiko, Shimada, Hiroyuki, Coburn, Jeannine M., Chiu, Bill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163090/
https://www.ncbi.nlm.nih.gov/pubmed/32096344
http://dx.doi.org/10.1002/cam4.2936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163090/
https://www.ncbi.nlm.nih.gov/pubmed/32096344
http://dx.doi.org/10.1002/cam4.2936

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