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Local delivery of dinutuximab from lyophilized silk fibroin foams for treatment of an orthotopic neuroblastoma model
Immunotherapy targeting GD2 is a primary treatment for patients with high‐risk neuroblastoma. Dinutuximab is a monoclonal antibody with great clinical promise but is limited by side effects such as severe pain. Local delivery has emerged as a potential mechanism to deliver higher doses of therapeuti...
Autores principales: | Ornell, Kimberly J., Taylor, Jordan S., Zeki, Jasmine, Ikegaki, Naohiko, Shimada, Hiroyuki, Coburn, Jeannine M., Chiu, Bill |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163090/ https://www.ncbi.nlm.nih.gov/pubmed/32096344 http://dx.doi.org/10.1002/cam4.2936 |
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