Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation

The formation of silenced and condensed heterochromatin foci involves enrichment of heterochromatin protein 1 (HP1). HP1 can bridge chromatin segments and form liquid droplets, but the biophysical principles underlying heterochromatin compartmentalization in the cell nucleus are elusive. Here, we as...

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Detalles Bibliográficos
Autores principales: Erdel, Fabian, Rademacher, Anne, Vlijm, Rifka, Tünnermann, Jana, Frank, Lukas, Weinmann, Robin, Schweigert, Elisabeth, Yserentant, Klaus, Hummert, Johan, Bauer, Caroline, Schumacher, Sabrina, Al Alwash, Ahmad, Normand, Christophe, Herten, Dirk-Peter, Engelhardt, Johann, Rippe, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163299/
https://www.ncbi.nlm.nih.gov/pubmed/32101700
http://dx.doi.org/10.1016/j.molcel.2020.02.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163299/
https://www.ncbi.nlm.nih.gov/pubmed/32101700
http://dx.doi.org/10.1016/j.molcel.2020.02.005

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