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Mouse Heterochromatin Adopts Digital Compaction States without Showing Hallmarks of HP1-Driven Liquid-Liquid Phase Separation
The formation of silenced and condensed heterochromatin foci involves enrichment of heterochromatin protein 1 (HP1). HP1 can bridge chromatin segments and form liquid droplets, but the biophysical principles underlying heterochromatin compartmentalization in the cell nucleus are elusive. Here, we as...
Autores principales: | Erdel, Fabian, Rademacher, Anne, Vlijm, Rifka, Tünnermann, Jana, Frank, Lukas, Weinmann, Robin, Schweigert, Elisabeth, Yserentant, Klaus, Hummert, Johan, Bauer, Caroline, Schumacher, Sabrina, Al Alwash, Ahmad, Normand, Christophe, Herten, Dirk-Peter, Engelhardt, Johann, Rippe, Karsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163299/ https://www.ncbi.nlm.nih.gov/pubmed/32101700 http://dx.doi.org/10.1016/j.molcel.2020.02.005 |
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