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Tetranucleotide Microsatellite Mutational Behavior Assessed in Real Time: Implications for Future Microsatellite Panels

BACKGROUND & AIMS: Fifty percent of colorectal cancers show elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) and are associated with inflammation, metastasis, and poor patient outcome. EMAST results from interleukin 6–induced nuclear-to-cytosolic displacement of th...

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Detalles Bibliográficos
Autores principales: Raeker, Maide Ö., Pierre-Charles, Jovan, Carethers, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163322/
https://www.ncbi.nlm.nih.gov/pubmed/31982570
http://dx.doi.org/10.1016/j.jcmgh.2020.01.006