Safety, tolerability, pharmacokinetics and pharmacodynamics of parenterally administered dutogliptin: A prospective dose‐escalating trial

AIMS: Animal studies suggest that inhibition of dipeptidyl peptidase 4 (DPP‐IV) may improve heart function and survival after myocardial infarction by increasing cardiac myocytes’ regenerative capacity. Parenterally administered dutogliptin may provide continuous strong DPP‐IV inhibition to translat...

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Detalles Bibliográficos
Autores principales: Buchtele, Nina, Schwameis, Michael, Schoergenhofer, Christian, Derhaschnig, Ulla, Firbas, Christa, Karch, Rudolf, Nix, Darrell, Schenk, Roman, Jilma, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163368/
https://www.ncbi.nlm.nih.gov/pubmed/31912513
http://dx.doi.org/10.1111/bcp.14208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163368/
https://www.ncbi.nlm.nih.gov/pubmed/31912513
http://dx.doi.org/10.1111/bcp.14208

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