Population pharmacokinetic modelling of busulfan and the influence of body composition in paediatric Fanconi anaemia patients

AIMS: Fanconi anaemia (FA) is a rare disorder characterized by progressive bone marrow failure that requires haematopoietic cell transplantation (HCT). Busulfan is used in conditioning regimens prior to HCT. Doses used in non‐FA patients cause life‐threatening toxicities in FA patients and data on b...

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Detalles Bibliográficos
Autores principales: van Hoogdalem, Matthijs W., Emoto, Chie, Fukuda, Tsuyoshi, Mizuno, Tomoyuki, Mehta, Parinda A., Vinks, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163375/
https://www.ncbi.nlm.nih.gov/pubmed/31851762
http://dx.doi.org/10.1111/bcp.14202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163375/
https://www.ncbi.nlm.nih.gov/pubmed/31851762
http://dx.doi.org/10.1111/bcp.14202

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