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Down-regulation of FTO promotes proliferation and migration, and protects bladder cancer cells from cisplatin-induced cytotoxicity

BACKGROUND: FTO is known to be associated with body mass and obesity in humans and its over-expression affects the energy metabolism of cancer cells. The aim of the present study is to investigate the biological role of FTO in human bladder urothelial carcinoma. METHODS: PCR and western blotting are...

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Detalles Bibliográficos
Autores principales: Wen, Lijie, Pan, Xianwei, Yu, Yang, Yang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164175/
https://www.ncbi.nlm.nih.gov/pubmed/32299393
http://dx.doi.org/10.1186/s12894-020-00612-7