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CD4+ T cell expression of the IL-10 receptor is necessary for facial motoneuron survival after axotomy

BACKGROUND: After peripheral nerve transection, facial motoneuron (FMN) survival depends on an intact CD4+ T cell population and a central source of interleukin-10 (IL-10). However, it has not been determined previously whether CD4+ T cells participate in the central neuroprotective IL-10 cascade af...

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Detalles Bibliográficos
Autores principales: Runge, Elizabeth M., Iyer, Abhirami K., Setter, Deborah O., Kennedy, Felicia M., Sanders, Virginia M., Jones, Kathryn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164177/
https://www.ncbi.nlm.nih.gov/pubmed/32303238
http://dx.doi.org/10.1186/s12974-020-01772-x