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Ionizing radiation modulates the phenotype and function of human CD4+ induced regulatory T cells

BACKGROUND: The use of immunotherapy strategies for the treatment of advanced cancer is rapidly increasing. Most immunotherapies rely on induction of CD8+ tumor-specific cytotoxic T cells that are capable of directly killing cancer cells. Tumors, however, utilize a variety of mechanisms that can sup...

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Detalles Bibliográficos
Autores principales: Beauford, Samantha S., Kumari, Anita, Garnett-Benson, Charlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164225/
https://www.ncbi.nlm.nih.gov/pubmed/32299365
http://dx.doi.org/10.1186/s12865-020-00349-w