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Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson’s disease brain

BACKGROUND: Many lines of evidence suggest that accumulation of aggregated alpha-synuclein (αSYN) in the Parkinson’s disease (PD) brain causes infiltration of T cells. However, in which ways the stationary brain cells interact with the T cells remain elusive. Here, we identify astrocytes as potentia...

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Detalles Bibliográficos
Autores principales: Rostami, Jinar, Fotaki, Grammatiki, Sirois, Julien, Mzezewa, Ropafadzo, Bergström, Joakim, Essand, Magnus, Healy, Luke, Erlandsson, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164247/
https://www.ncbi.nlm.nih.gov/pubmed/32299492
http://dx.doi.org/10.1186/s12974-020-01776-7