Merlin regulates signaling events at the nexus of development and cancer

BACKGROUND: In this review, we describe how the cytoskeletal protein Merlin, encoded by the Neurofibromin 2 (NF2) gene, orchestrates developmental signaling to ensure normal ontogeny, and we discuss how Merlin deficiency leads to aberrant activation of developmental pathways that enable tumor develo...

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Detalles Bibliográficos
Autores principales: Mota, Mateus, Shevde, Lalita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164249/
https://www.ncbi.nlm.nih.gov/pubmed/32299434
http://dx.doi.org/10.1186/s12964-020-00544-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164249/
https://www.ncbi.nlm.nih.gov/pubmed/32299434
http://dx.doi.org/10.1186/s12964-020-00544-7

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