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The analgesic action of larixyl acetate, a potent TRPC6 inhibitor, in rat neuropathic pain model induced by spared nerve injury

BACKGROUND: Neuropathic pain is a debilitating status that is insusceptible to the existing analgesics. It is important to explore the underlying pathophysiological changes and search for new pharmacological approaches. Transient receptor potential canonical 6 (TRPC6) is a mechanosensitive channel t...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Zhao, Ming, Jia, Peng, Liu, Fang-Fang, Chen, Kun, Meng, Fei-Yang, Hong, Jiang-Hao, Zhang, Ting, Jin, Xiao-Hang, Shi, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164269/
https://www.ncbi.nlm.nih.gov/pubmed/32299452
http://dx.doi.org/10.1186/s12974-020-01767-8