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Variations in 5-methylcytosine and 5-hydroxymethylcytosine among human brain, blood, and saliva using oxBS and the Infinium MethylationEPIC array

Investigating 5-methylcytosine (5mC) has led to many hypotheses regarding molecular mechanism underlying human diseases and disorders. Many of these studies, however, utilize bisulfite conversion alone, which cannot distinguish 5mC from its recently discovered oxidative product, 5-hydroxymethylcytos...

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Detalles Bibliográficos
Autores principales: Gross, Jeffrey A., Lefebvre, François, Lutz, Pierre-Eric, Bacot, François, Vincent, Daniel, Bourque, Guillaume, Turecki, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164292/
https://www.ncbi.nlm.nih.gov/pubmed/32328532
http://dx.doi.org/10.1093/biomethods/bpw002