Frequent alterations in p16/CDKN2A identified by immunohistochemistry and FISH in chordoma

The expression of p16/CDKN2A, the second most commonly inactivated tumour suppressor gene in cancer, is lost in the majority of chordomas. However, the mechanism(s) leading to its inactivation and contribution to disease progression have only been partially addressed using small patient cohorts. We...

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Detalles Bibliográficos
Autores principales: Cottone, Lucia, Eden, Nadia, Usher, Inga, Lombard, Patrick, Ye, Hongtao, Ligammari, Lorena, Lindsay, Daniel, Brandner, Sebastian, Pižem, Jože, Pillay, Nischalan, Tirabosco, Roberto, Amary, Fernanda, Flanagan, Adrienne M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164370/
https://www.ncbi.nlm.nih.gov/pubmed/31916407
http://dx.doi.org/10.1002/cjp2.156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164370/
https://www.ncbi.nlm.nih.gov/pubmed/31916407
http://dx.doi.org/10.1002/cjp2.156

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