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Biomarker recommendation for PD‐1/PD‐L1 immunotherapy development in pediatric cancer based on digital image analysis of PD‐L1 and immune cells

Anti‐PD‐1/PD‐L1 immunotherapy could offer an alternative to traditional chemo‐ and/or radiotherapy to treat pediatric cancer patients. To unveil the potential benefit of this new therapeutic approach, the prevalence of PD‐L1 and other relevant immune markers using quantitative digital image analysis...

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Detalles Bibliográficos
Autores principales: Silva, Manuel A, Triltsch, Nicolas, Leis, Simon, Kanchev, Ivan, Tan, Tze Heng, Van Peel, Benjamine, Van Kerckhoven, Marian, Deschoolmeester, Vanessa, Zimmermann, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164376/
https://www.ncbi.nlm.nih.gov/pubmed/31922656
http://dx.doi.org/10.1002/cjp2.152