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DNA nanovaccines prepared using LemA antigen protect Golden Syrian hamsters against Leptospira lethal infection

BACKGROUND: Nanoparticles (NPs) are viable candidates as carriers of exogenous materials into cells via transfection and can be used in the DNA vaccination strategy against leptospirosis. OBJECTIVES: We evaluated the efficiency of halloysite clay nanotubes (HNTs) and amine-functionalised multi-walle...

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Detalles Bibliográficos
Autores principales: Oliveira, Thaís Larré, Bacelo, Kátia Leston, Forster, Karine Maciel, Ilha, Vinicius, Rodrigues, Oscar Endrigo, Hartwig, Daiane D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164400/
https://www.ncbi.nlm.nih.gov/pubmed/32321154
http://dx.doi.org/10.1590/0074-02760190396