Relative bioavailability of a pediatric dispersible tablet and adult film‐coated tablet of macitentan in healthy volunteers

To compare the pharmacokinetic (PK) properties of the pediatric dispersible tablet formulation of macitentan and the adult film‐coated tablet formulation of macitentan in healthy subjects. A randomized, open‐label, single‐dose, two‐sequence, two‐period, crossover, Phase 1 study was conducted in 12 h...

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Detalles Bibliográficos
Autores principales: Sidharta, Patricia N., Štěpánová, Radka, Globig, Susanne, Ulč, Ivan, Csonka, Dénes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164404/
https://www.ncbi.nlm.nih.gov/pubmed/32302056
http://dx.doi.org/10.1002/prp2.580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164404/
https://www.ncbi.nlm.nih.gov/pubmed/32302056
http://dx.doi.org/10.1002/prp2.580

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