β2‐adrenergic stimulation induces interleukin‐6 by increasing Arid5a, a stabilizer of mRNA, through cAMP/PKA/CREB pathway in cardiac fibroblasts

BACKGROUND AND PURPOSE: In cardiovascular diseases, cardiac fibroblasts (CFs) participate in the myocardial inflammation by producing pro‐inflammatory cytokines, worsening the prognosis. β2‐adrenergic receptor (AR) and β3AR are expressed in CFs, and β‐adrenergic stimulation promotes CFs to produce p...

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Detalles Bibliográficos
Autores principales: Tanaka, Shota, Imaeda, Atsuki, Matsumoto, Kotaro, Maeda, Makiko, Obana, Masanori, Fujio, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164407/
https://www.ncbi.nlm.nih.gov/pubmed/32302067
http://dx.doi.org/10.1002/prp2.590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164407/
https://www.ncbi.nlm.nih.gov/pubmed/32302067
http://dx.doi.org/10.1002/prp2.590

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