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β2‐adrenergic stimulation induces interleukin‐6 by increasing Arid5a, a stabilizer of mRNA, through cAMP/PKA/CREB pathway in cardiac fibroblasts
BACKGROUND AND PURPOSE: In cardiovascular diseases, cardiac fibroblasts (CFs) participate in the myocardial inflammation by producing pro‐inflammatory cytokines, worsening the prognosis. β2‐adrenergic receptor (AR) and β3AR are expressed in CFs, and β‐adrenergic stimulation promotes CFs to produce p...
Autores principales: | Tanaka, Shota, Imaeda, Atsuki, Matsumoto, Kotaro, Maeda, Makiko, Obana, Masanori, Fujio, Yasushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164407/ https://www.ncbi.nlm.nih.gov/pubmed/32302067 http://dx.doi.org/10.1002/prp2.590 |
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