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Checking responses of goal- and sign-trackers are differentially affected by threat in a rodent analog of obsessive–compulsive disorder

In obsessive–compulsive disorder (OCD), functional behaviors such as checking that a door is locked become dysfunctional, maladaptive, and debilitating. However, it is currently unknown how aversive and appetitive motivations interact to produce functional and dysfunctional behavior in OCD. Here we...

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Detalles Bibliográficos
Autores principales: Vousden, George H., Paulcan, Sloane, Robbins, Trevor W., Eagle, Dawn M., Milton, Amy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164513/
https://www.ncbi.nlm.nih.gov/pubmed/32295839
http://dx.doi.org/10.1101/lm.050260.119