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Neuroprotective effects of exogenous erythropoietin in Wistar rats by downregulating apoptotic factors to attenuate N-methyl-D-aspartate-mediated retinal ganglion cells death

The aim of this study was to investigate whether exogenous erythropoietin (EPO) administration attenuates N-methyl-D-aspartate (NMDA)-mediated excitotoxic retinal damage in Wistar rats. The survival rate of retinal ganglion cells (RGCs) were investigated by flat mount analysis and flow cytometry. A...

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Detalles Bibliográficos
Autores principales: Cheng, Wen-Sheng, Lin, I-Hung, Feng, Kathy Ming, Chang, Zhi-Yang, Huang, Yu Chuan, Lu, Da-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164594/
https://www.ncbi.nlm.nih.gov/pubmed/32302311
http://dx.doi.org/10.1371/journal.pone.0223208