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Streptococcal H(2)O(2) inhibits IgE-triggered degranulation of RBL-2H3 mast cell/basophil cell line by inducing cell death

Mast cells and basophils are central players in allergic reactions triggered by immunoglobulin E (IgE). They have intracellular granules containing allergic mediators (e.g., histamine, serotonin, inflammatory cytokines, proteases and β-hexosaminidase), and stimulation by IgE-allergen complex leads t...

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Detalles Bibliográficos
Autores principales: Okahashi, Nobuo, Nakata, Masanobu, Hirose, Yujiro, Morisaki, Hirobumi, Kataoka, Hideo, Kuwata, Hirotaka, Kawabata, Shigetada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164662/
https://www.ncbi.nlm.nih.gov/pubmed/32302339
http://dx.doi.org/10.1371/journal.pone.0231101