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Dual metabolomic profiling uncovers Toxoplasma manipulation of the host metabolome and the discovery of a novel parasite metabolic capability

The obligate intracellular parasite Toxoplasma gondii is auxotrophic for several key metabolites and must scavenge these from the host. It is unclear how T. gondii manipulates host metabolism to support its overall growth rate and non-essential metabolites. To investigate this question, we measured...

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Detalles Bibliográficos
Autores principales: Olson, William J., Martorelli Di Genova, Bruno, Gallego-Lopez, Gina, Dawson, Anthony R., Stevenson, David, Amador-Noguez, Daniel, Knoll, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164669/
https://www.ncbi.nlm.nih.gov/pubmed/32255806
http://dx.doi.org/10.1371/journal.ppat.1008432