Cargando…
Cobalt ion interaction with TMEM16A calcium-activated chloride channel: Inhibition and potentiation
TMEM16A, a Ca(2+)-sensitive Cl(-) channel, plays key roles in many physiological functions related to Cl(-) transport across lipid membranes. Activation of this channel is mediated via binding intracellular Ca(2+) to the channel with a relatively high apparent affinity, roughly in the sub-μM to low...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164836/ https://www.ncbi.nlm.nih.gov/pubmed/32302365 http://dx.doi.org/10.1371/journal.pone.0231812 |