uPAR antibody (huATN-658) and Zometa reduce breast cancer growth and skeletal lesions

Urokinase plasminogen activator receptor (uPAR) is implicated in tumor growth and metastasis due to its ability to activate latent growth factors, proteases, and different oncogenic signaling pathways upon binding to different ligands. Elevated uPAR expression is correlated with the increased aggres...

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Detalles Bibliográficos
Autores principales: Mahmood, Niaz, Arakelian, Ani, Khan, Haseeb Ahmed, Tanvir, Imrana, Mazar, Andrew P., Rabbani, Shafaat A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165173/
https://www.ncbi.nlm.nih.gov/pubmed/32337090
http://dx.doi.org/10.1038/s41413-020-0094-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165173/
https://www.ncbi.nlm.nih.gov/pubmed/32337090
http://dx.doi.org/10.1038/s41413-020-0094-3

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