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uPAR antibody (huATN-658) and Zometa reduce breast cancer growth and skeletal lesions
Urokinase plasminogen activator receptor (uPAR) is implicated in tumor growth and metastasis due to its ability to activate latent growth factors, proteases, and different oncogenic signaling pathways upon binding to different ligands. Elevated uPAR expression is correlated with the increased aggres...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165173/ https://www.ncbi.nlm.nih.gov/pubmed/32337090 http://dx.doi.org/10.1038/s41413-020-0094-3 |