Combinatorial control of Spo11 alternative splicing by modulation of RNA polymerase II dynamics and splicing factor recruitment during meiosis

Homologous recombination and chromosome segregation in meiosis rely on the timely expression of two splice variants of the endonuclease SPO11, named α and β, which respectively skip or include exon 2. However, in spite of its physiological importance, the mechanism underlying Spo11 alternative splic...

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Detalles Bibliográficos
Autores principales: Cesari, Eleonora, Loiarro, Maria, Naro, Chiara, Pieraccioli, Marco, Farini, Donatella, Pellegrini, Livia, Pagliarini, Vittoria, Bielli, Pamela, Sette, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165175/
https://www.ncbi.nlm.nih.gov/pubmed/32303676
http://dx.doi.org/10.1038/s41419-020-2443-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165175/
https://www.ncbi.nlm.nih.gov/pubmed/32303676
http://dx.doi.org/10.1038/s41419-020-2443-y

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