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Blocking GSDMD processing in innate immune cells but not in hepatocytes protects hepatic ischemia–reperfusion injury
Pyroptosis, a proinflammatory form of programmed cell death, plays important roles in the pathogenesis of many diseases. Inflammasome activation, which has been shown in hepatic ischemia–reperfusion injury (IRI), is demonstrated to be closely associated with pyroptosis, indicating that pyroptosis ma...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165177/ https://www.ncbi.nlm.nih.gov/pubmed/32303674 http://dx.doi.org/10.1038/s41419-020-2437-9 |