Blocking GSDMD processing in innate immune cells but not in hepatocytes protects hepatic ischemia–reperfusion injury

Pyroptosis, a proinflammatory form of programmed cell death, plays important roles in the pathogenesis of many diseases. Inflammasome activation, which has been shown in hepatic ischemia–reperfusion injury (IRI), is demonstrated to be closely associated with pyroptosis, indicating that pyroptosis ma...

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Detalles Bibliográficos
Autores principales: Li, Jichang, Zhao, Jie, Xu, Min, Li, Meng, Wang, Bingrui, Qu, Xiaoye, Yu, Chang, Hang, Hualian, Xia, Qiang, Wu, Hailong, Sun, Xuehua, Gu, Jinyang, Kong, Xiaoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165177/
https://www.ncbi.nlm.nih.gov/pubmed/32303674
http://dx.doi.org/10.1038/s41419-020-2437-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165177/
https://www.ncbi.nlm.nih.gov/pubmed/32303674
http://dx.doi.org/10.1038/s41419-020-2437-9

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