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Prostaglandin E2 stimulates COX-2 expression via mitogen-activated protein kinase p38 but not ERK in human follicular dendritic cell-like cells

BACKGROUND: Prostaglandin E2 (PGE(2)) is an endogenous lipid mediator of inflammation. Its production is regulated by the rate-limiting upstream enzyme cyclooxygenase-2 (COX-2). We have recently demonstrated that the major cell type expressing COX-2 in the germinal center is follicular dendritic cel...

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Detalles Bibliográficos
Autores principales: Cho, Whajung, Choe, Jongseon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165408/
https://www.ncbi.nlm.nih.gov/pubmed/32303181
http://dx.doi.org/10.1186/s12865-020-00347-y