Modulation of androgen receptor DNA binding activity through direct interaction with the ETS transcription factor ERG

The androgen receptor (AR) is a type I nuclear hormone receptor and the primary drug target in prostate cancer due to its role as a lineage survival factor in prostate luminal epithelium. In prostate cancer, the AR cistrome is reprogrammed relative to normal prostate epithelium and particularly in c...

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Detalles Bibliográficos
Autores principales: Wasmuth, Elizabeth V., Hoover, Elizabeth A., Antar, Albert, Klinge, Sebastian, Chen, Yu, Sawyers, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165421/
https://www.ncbi.nlm.nih.gov/pubmed/32220959
http://dx.doi.org/10.1073/pnas.1922159117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165421/
https://www.ncbi.nlm.nih.gov/pubmed/32220959
http://dx.doi.org/10.1073/pnas.1922159117

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