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Modulation of androgen receptor DNA binding activity through direct interaction with the ETS transcription factor ERG
The androgen receptor (AR) is a type I nuclear hormone receptor and the primary drug target in prostate cancer due to its role as a lineage survival factor in prostate luminal epithelium. In prostate cancer, the AR cistrome is reprogrammed relative to normal prostate epithelium and particularly in c...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165421/ https://www.ncbi.nlm.nih.gov/pubmed/32220959 http://dx.doi.org/10.1073/pnas.1922159117 |